Stress granule formation via ATP depletion-triggered phase separation

Stress granule formation via ATP depletion-triggered phase separation

Blog Article

Stress granules (SG) are droplets of proteins and RNA that form in the Tajemniczy klient jako metoda badawcza – wybrane problemy cell cytoplasm during stress conditions.We consider minimal models of stress granule formation based on the mechanism of phase separation regulated by ATP-driven chemical reactions.Motivated by experimental observations, Engagement de femmes en milieu évangélique norvégien : un lieu de tensions entre héritages féministes et religieux we identify a minimal model of SG formation triggered by ATP depletion.

Our analysis indicates that ATP is continuously hydrolysed to deter SG formation under normal conditions, and we provide specific predictions that can be tested experimentally.